May 7, 2012

HELIX BIOPHARMA CORP. UPDATES SHAREHOLDERS ON COURT APPROVAL OF SETTLEMENT (PDF)

(Aurora, Ontario) – Helix BioPharma Corp. (TSX, NYSE Amex, FSE: “HBP”) announced today that it has obtained an Order of
the Ontario Superior Court of Justice approving the settlement that Helix entered into with the Concerned Shareholders and others on March 14, 2012, and dismissing the related court proceedings. Among other things, the approved settlement specifies the composition of Helix’s current, reconstituted, board of directors, and provides that Helix’s next annual general meeting of shareholders will not be held prior to January 15, 2013.